Cytokinetics, Inc. (NASDAQ:CYTK) Earnings Preview: What Investors Need to Know

Font: Financial Modeling Prep  • Feb 23, 2026

Cytokinetics, Inc. (NASDAQ:CYTK) is a biopharmaceutical company focused on developing treatments for cardiovascular diseases. With over 25 years of expertise in muscle biology, the company aims to innovate in the field of cardiac medicine. As it prepares to release its fourth-quarter earnings on February 24, 2026, investors are keenly watching the anticipated financial results.

Wall Street estimates that CYTK will report an earnings per share (EPS) of -$1.48, with revenue expected to be around $8.02 million. This aligns with the Zacks Consensus Estimate, which also predicts a quarterly loss of $1.48 per share. The anticipated decline in earnings and revenue compared to the previous year suggests that the company may not achieve an earnings beat in its upcoming report.

Cytokinetics' financial metrics reveal some challenges. The company has a negative price-to-earnings (P/E) ratio of -10.86, indicating it is not currently profitable. Additionally, the price-to-sales ratio is approximately 95.39, suggesting that investors are paying a high price for each dollar of sales. The enterprise value to sales ratio is around 106.53, reflecting a premium valuation relative to its sales.

Despite these challenges, Cytokinetics maintains a strong current ratio of 6.88, indicating its ability to cover short-term liabilities with short-term assets. However, the enterprise value to operating cash flow ratio of -21.46 highlights difficulties in generating positive cash flow from operations. The debt-to-equity ratio of -2.30 suggests more liabilities than equity, which could be a concern for investors.

The upcoming earnings call, scheduled for 4:30 PM Eastern Time on February 24, will be crucial. Management's discussion will provide insights into the sustainability of any immediate stock price changes and future earnings expectations. Investors can access the live webcast through the company's website, with an archived replay available for six months.